January 26, 2019
CRISPR used to control which genes are passed down in mice
CRISPR used to control which genes are passed down in mice
Biologists at the University of California San Diego have successfully used the CRISPR gene-editing tool to control genetic inheritance in mice for the first time. In this case, the researchers engineered an active genetic “CopyCat” DNA element, and used CRISPR to copy it from one chromosome to the other. The idea is that this would increase the chances that this gene would be passed down to the next generation of mice in tests. In recent years a similar process has been used in insects, for example in making malaria-resistant mosquitoes that will pass that trait down through a population