December 10, 2017
First semi-synthetic bacteria with artificial DNA has created an entirely novel protein
First semi-synthetic bacteria with artificial DNA has created an entirely novel protein
For several years, the research team has worked on creating a stable, living organism with new, unnatural DNA base pairs. The synthetic bases, dubbed “X” and “Y”, were added into the DNA of a strain of E. coli bacteria. Earlier in 2017, the team revealed that after several unsuccessful attempts, it had finally stabilized the semi-synthetic bacteria, and got it to grow and divide naturally, passing on the synthetic “X” and “Y” bases to new generations. And now the creation of a completely new and unnatural protein has been effectively demonstrated with the semi-synthetic organism expressing a variant of green fluorescent protein